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Paul, it's "oesophagus"!
The reason they stopped giving aspirin as a plain pain killer, is because, I think I'm right in saying, some people were having a severe reaction (mainly children).
It is given in small doses to prevent strokes.
The therapeutic dose is 75mg per day, but the normal strength was 300mg and taken 3 or 4 times a day for a prolonged period often caused bleeding.
It is fantastic stuff, and all from the bark of the willow tree (at least originally)
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